Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TGAM_0278Conserved hypothetical protein; UPF0153 family. (175 aa)    
Predicted Functional Partners:
TGAM_0279
Ribosome subunit biogenesis protein, putative; Belongs to UPF0113 family.
       0.914
TGAM_0276
Histone acetyltransferase-like protein; Contains Elp3 (Elongator protein 3), belongs to GNAT methyltransferases family.
       0.860
TGAM_0277
Conserved hypothetical protein; 1 probable transmembrane helix predicted by modhmm.
       0.843
TGAM_0280
RecA-superfamily ATPase, Rad55-like protein; Contains 1 P_Loop (SSF52540) domain, 1 Kaic (PF06745) domain; Belongs to the UPF0273 family.
       0.819
TGAM_0281
Conserved hypothetical protein, predicted transcriptional regulator.
       0.789
TGAM_0274
NIF3 (NGG1p interacting factor 3)-like protein.
 
     0.774
TGAM_0182
AAA family ATPase, possibly ruvB related.
 
     0.548
nusA-1
Transcription elongation factor, putative NusA-like protein (nusA); Contains 1 KH domain.
 
     0.502
TGAM_1847
Conserved hypothetical protein.
  
     0.453
TGAM_0275
Prokaryotic ATPase, AAA superfamily; Contains Archaeal ATPase domain (PF01637).
       0.447
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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