Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TGAM_0280RecA-superfamily ATPase, Rad55-like protein; Contains 1 P_Loop (SSF52540) domain, 1 Kaic (PF06745) domain; Belongs to the UPF0273 family. (248 aa)    
Predicted Functional Partners:
TGAM_0281
Conserved hypothetical protein, predicted transcriptional regulator.
     
 0.893
TGAM_0279
Ribosome subunit biogenesis protein, putative; Belongs to UPF0113 family.
       0.834
TGAM_0278
Conserved hypothetical protein; UPF0153 family.
       0.819
TGAM_0277
Conserved hypothetical protein; 1 probable transmembrane helix predicted by modhmm.
       0.548
TGAM_0276
Histone acetyltransferase-like protein; Contains Elp3 (Elongator protein 3), belongs to GNAT methyltransferases family.
       0.531
rgy
Reverse gyrase (rgy); Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
 
     0.400
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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