Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
trkATrk system potassium uptake protein trkA-like protein (trkA). (228 aa)    
Predicted Functional Partners:
trkG/H
Potassium uptake protein, TrkH family (trkG/H); 12 probable transmembrane helices predicted by modhmm.
 
 
 0.976
secDF
Protein export membrane protein, SecD/SecF family (secDF); Involved in protein export.
 
     0.887
secD
Protein-export membrane protein (secD); Involved in protein export.
       0.866
moaE
moaE molybdopterin synthase, large chain (moaE).
  
    0.854
TGAM_1855
Amino acid transporter; 12 probable transmembrane helices predicted by modhmm.
  
  
 0.830
speH
S-adenosylmethionine decarboxylase proenzyme (speH); Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
     
 0.753
atpK
Archaeal/vacuolar-type H+-ATPase, subunit K (atpK); 4 probable transmembrane helices predicted by modhmm.
 
   
 0.737
fba
Fructose 1,6-bisphosphate aldolase class 1 (fba).
   
  
 0.701
atpC
Archaeal/vacuolar-type H+ ATPase, subunit C (atpC); Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
     0.696
atpI
Archaeal/vacuolar-type H+-ATPase subunit I (atpI); 7 probable transmembrane helices predicted by modhmm; Belongs to the V-ATPase 116 kDa subunit family.
 
     0.690
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
Server load: low (28%) [HD]