Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TGAM_0290tRNA/rRNA cytosine-C5-methylase, putative; Belongs to Sun/NOL1/NOP family. Contains 1 PUA domain and 1 SAM binding domain; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (389 aa)    
Predicted Functional Partners:
TGAM_0291
Conserved hypothetical protein.
       0.916
TGAM_0289
Conserved hypothetical protein; Belongs to UPF0104 family; 8 probable transmembrane helices predicted by modhmm.
       0.914
TGAM_0292
Conserved hypothetical protein; 1 probable transmembrane helix predicted by modhmm.
       0.863
arcTGT
Archaeosine tRNA-guanine transglycosylase (ArcTGT); Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
  
  
 0.794
TGAM_0464
pre-mRNA splicing, snoRNA binding protein, NOP5/NOP56 related.
  
 
 0.726
TGAM_0279
Ribosome subunit biogenesis protein, putative; Belongs to UPF0113 family.
  
 
 0.669
ppnK
Inorganic polyphosphate/ATP-NAD kinase (poly(P)/ATP NAD kinase) (ppnK); Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
    0.660
TGAM_0201
GTP-binding protein, HSR1-related GTPase; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
  
 
 0.628
carS
Conserved hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids.
  
    0.621
TGAM_0293
Oxidoreductase; FAD/NAD(P)-binding Rossmann fold Superfamily protein.
 
     0.616
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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