Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TGAM_0293Oxidoreductase; FAD/NAD(P)-binding Rossmann fold Superfamily protein. (487 aa)    
Predicted Functional Partners:
TGAM_0292
Conserved hypothetical protein; 1 probable transmembrane helix predicted by modhmm.
       0.718
TGAM_0302
Conserved hypothetical protein; Contains CBS domain pair (PF00571).
       0.649
napA-1
Na+/H+ antiporter, napA type (napA); 11 probable transmembrane helices predicted by modhmm.
       0.649
TGAM_2130
PP-loop ATPase, YdaO-type.
       0.649
TGAM_0290
tRNA/rRNA cytosine-C5-methylase, putative; Belongs to Sun/NOL1/NOP family. Contains 1 PUA domain and 1 SAM binding domain; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
 
     0.616
TGAM_0289
Conserved hypothetical protein; Belongs to UPF0104 family; 8 probable transmembrane helices predicted by modhmm.
       0.565
TGAM_0291
Conserved hypothetical protein.
       0.565
TGAM_0294
Hypothetical protein; 2 probable transmembrane helices predicted by modhmm.
       0.554
TGAM_0295
Hypothetical protein; 5 probable transmembrane helices predicted by modhmm.
       0.554
purP
IMP biosynthesis enzyme (5-formaminoimidazole-4-carboxamide-1-(beta)-D- ribofuranosyl 5'-monophosphate synthetase) (purP).
 
     0.408
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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