Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ttdBFumarate hydratase class I, C-terminal domain (ttdB). (169 aa)    
Predicted Functional Partners:
ttdA
Fumarate hydratase class I, N-terminal domain (ttdA).
 0.999
maeB
Malic enzyme (malate oxidoreductase) (maeB).
 
 
 0.981
TGAM_1022
Iron-sulfur binding reductase.
    
 0.912
aspC-2
Aspartate aminotransferase (aspC).
    
 0.808
aspC-3
Aspartate aminotransferase (aspC).
    
 0.808
mhy2B
Formate hydrogenlyase II subunit B (Mhy2B); Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
    
 0.806
fdh1B
Formate dehydrogenase I subunit B (fdh1B).
    
 0.806
serA
D-3-phosphoglycerate dehydrogenase, putative (serA); Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
     
 0.746
TGAM_0321
Phosphate transport regulator, putative; Belongs to DUF47 family, PhoU/Pit related.
       0.744
panE
2-dehydropantoate reductase (panE); Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
  
    0.739
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.