STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
TGAM_0331Solute binding protein, putative; Contains Periplasmic binding protein-like II domain (SSF53850); 2 probable transmembrane helices predicted by modhmm. (845 aa)    
Predicted Functional Partners:
dppB
Peptide/nickel transport system permease protein; 6 probable transmembrane helices predicted by modhmm.
 
  
  0.984
dppC
Peptide/nickel transport system permease protein; 6 probable transmembrane helices predicted by modhmm.
 
     0.866
dppD
ABC-type dipeptide/oligopeptide transport system, ATPase component (dppD/oppD).
 
     0.828
pyrK
Dihydroorotate dehydrogenase electron transfer subunit (pyrK); Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
       0.816
TGAM_0337
Drug/Metabolite transporter, putative; Belongs to DUF6 family; 10 probable transmembrane helices predicted by modhmm.
 
     0.815
pyrC
Dihydroorotase (pyrC); Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
       0.812
dppF
ABC-type dipeptide/oligopeptide transport system, ATPase component (dppF/oppF).
       0.794
TGAM_0336
Conserved hypothetical protein; 2 probable transmembrane helices predicted by modhmm.
       0.794
nadE
NH(3)-dependent NAD synthetase (nadE); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
 
     0.652
TGAM_0573
Conserved hypothetical protein; 2 probable transmembrane helices predicted by modhmm.
  
     0.621
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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