Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pdhxProline dehydrogenase, delta subunit (pdhx). (90 aa)    
Predicted Functional Partners:
pdha
Proline dehydrogenase, alpha subunit (pdha).
 
   
 0.975
pdhf
Proline dehydrogenase, gamma subunit (pdhf).
 
   
 0.975
pdhb
Proline dehydrogenase, beta subunit (pdhb).
 
 
 0.967
soxB
Sarcosine oxidase, subunit beta (SoxB).
 
 
 0.885
pyrH
Uridylate kinase (pyrH); Catalyzes the reversible phosphorylation of UMP to UDP.
  
    0.758
cydA
Cytochrome bd ubiquinol oxidase, subunit I (cydA); 9 probable transmembrane helices predicted by modhmm.
  
 
 0.560
soxA
Sarcosine oxidase, subunit alpha (SoxA).
       0.467
TGAM_1236
Conserved hypothetical protein; Belongs to DUF1641 family.
  
    0.430
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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