kptA protein (Thermococcus gammatolerans) - STRING interaction network

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kptA

RNA 2'-phosphotransferase (kptA); Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase. (179 aa)

Predicted Functional Partners:

TGAM_0365

0.878

queE

0.845

nox

0.814

pyrH

0.652

pyrF

0.615

Your Current Organism:

Thermococcus gammatolerans

NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TGAM_0365	kptA	TGAM_0365	TGAM_0366	Metal-dependent hydrolase; Contains 1 Endonuclease/exonuclease/phosphatase (PF03372) domain; 10 probable transmembrane helices predicted by modhmm.	RNA 2'-phosphotransferase (kptA); Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase.	0.878
TGAM_0365	nox	TGAM_0365	TGAM_0364	Metal-dependent hydrolase; Contains 1 Endonuclease/exonuclease/phosphatase (PF03372) domain; 10 probable transmembrane helices predicted by modhmm.	NADH oxidase (NOXase) (nox).	0.843
TGAM_0365	pyrH	TGAM_0365	TGAM_0361	Metal-dependent hydrolase; Contains 1 Endonuclease/exonuclease/phosphatase (PF03372) domain; 10 probable transmembrane helices predicted by modhmm.	Uridylate kinase (pyrH); Catalyzes the reversible phosphorylation of UMP to UDP.	0.513
kptA	TGAM_0365	TGAM_0366	TGAM_0365	RNA 2'-phosphotransferase (kptA); Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase.	Metal-dependent hydrolase; Contains 1 Endonuclease/exonuclease/phosphatase (PF03372) domain; 10 probable transmembrane helices predicted by modhmm.	0.878
kptA	nox	TGAM_0366	TGAM_0364	RNA 2'-phosphotransferase (kptA); Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase.	NADH oxidase (NOXase) (nox).	0.814
kptA	pyrF	TGAM_0366	TGAM_1846	RNA 2'-phosphotransferase (kptA); Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase.	Orotidine 5'-phosphate decarboxylase (pyrF); Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.	0.615
kptA	pyrH	TGAM_0366	TGAM_0361	RNA 2'-phosphotransferase (kptA); Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase.	Uridylate kinase (pyrH); Catalyzes the reversible phosphorylation of UMP to UDP.	0.652
kptA	queE	TGAM_0366	TGAM_1325	RNA 2'-phosphotransferase (kptA); Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase.	Radical SAM protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.	0.845
nox	TGAM_0365	TGAM_0364	TGAM_0365	NADH oxidase (NOXase) (nox).	Metal-dependent hydrolase; Contains 1 Endonuclease/exonuclease/phosphatase (PF03372) domain; 10 probable transmembrane helices predicted by modhmm.	0.843
nox	kptA	TGAM_0364	TGAM_0366	NADH oxidase (NOXase) (nox).	RNA 2'-phosphotransferase (kptA); Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase.	0.814
nox	pyrH	TGAM_0364	TGAM_0361	NADH oxidase (NOXase) (nox).	Uridylate kinase (pyrH); Catalyzes the reversible phosphorylation of UMP to UDP.	0.800
pyrF	kptA	TGAM_1846	TGAM_0366	Orotidine 5'-phosphate decarboxylase (pyrF); Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.	RNA 2'-phosphotransferase (kptA); Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase.	0.615
pyrF	pyrH	TGAM_1846	TGAM_0361	Orotidine 5'-phosphate decarboxylase (pyrF); Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.	Uridylate kinase (pyrH); Catalyzes the reversible phosphorylation of UMP to UDP.	0.936
pyrF	queE	TGAM_1846	TGAM_1325	Orotidine 5'-phosphate decarboxylase (pyrF); Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.	Radical SAM protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.	0.546
pyrH	TGAM_0365	TGAM_0361	TGAM_0365	Uridylate kinase (pyrH); Catalyzes the reversible phosphorylation of UMP to UDP.	Metal-dependent hydrolase; Contains 1 Endonuclease/exonuclease/phosphatase (PF03372) domain; 10 probable transmembrane helices predicted by modhmm.	0.513
pyrH	kptA	TGAM_0361	TGAM_0366	Uridylate kinase (pyrH); Catalyzes the reversible phosphorylation of UMP to UDP.	RNA 2'-phosphotransferase (kptA); Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase.	0.652
pyrH	nox	TGAM_0361	TGAM_0364	Uridylate kinase (pyrH); Catalyzes the reversible phosphorylation of UMP to UDP.	NADH oxidase (NOXase) (nox).	0.800
pyrH	pyrF	TGAM_0361	TGAM_1846	Uridylate kinase (pyrH); Catalyzes the reversible phosphorylation of UMP to UDP.	Orotidine 5'-phosphate decarboxylase (pyrF); Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.	0.936
queE	kptA	TGAM_1325	TGAM_0366	Radical SAM protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.	RNA 2'-phosphotransferase (kptA); Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase.	0.845
queE	pyrF	TGAM_1325	TGAM_1846	Radical SAM protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.	Orotidine 5'-phosphate decarboxylase (pyrF); Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.	0.546

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