Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TGAM_0403Conserved hypothetical protein; Contains DUF137 domain. (270 aa)    
Predicted Functional Partners:
TGAM_1716
GHMP kinase, archaeal type, putative.
 
  
 0.985
coaBC
Coenzyme A biosynthesis bifunctional protein coaBC (coaBC); Includes Phosphopantothenoylcysteine decarboxylase and Phosphopantothenate--cysteine ligase.
 
  
 0.961
mfnA
L-tyrosine decarboxylase (mfnA); Catalyzes the decarboxylation of L-aspartate to produce beta- alanine; Belongs to the group II decarboxylase family. MfnA subfamily.
 
  
 0.951
TGAM_0179
Pyridoxal phosphate-dependent aminotransferase, class III family; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
  0.900
TGAM_0307
Pyridoxal phosphate-dependent aminotransferase, class III family; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
  0.900
TGAM_0402
Cytochrome-c3 hydrogenase, gamma subunit.
       0.819
TGAM_0400
Conserved hypothetical protein.
       0.602
TGAM_0866
Conserved hypothetical protein; Belongs to DUF81 family; Belongs to the UPF0201 family.
 
   
 0.574
gltA-1
Glutamate synthase (NADPH), homotetrameric (gltA).
       0.573
TGAM_0852
Nonsense-mediated mRNA decay protein, NMD3-like protein.
 
     0.462
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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