Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
TGAM_0404HTH-type transcriptional regulator, putative. (243 aa)    
Predicted Functional Partners:
TGAM_0461
3-hydroxy-3-methylglutaryl CoA synthase; Belongs to the thiolase-like superfamily. UPF0219 family.
  
    0.880
TGAM_0595
Radical-activating enzyme, pyruvate formate-lyase related.
  
     0.649
TGAM_0460
Acetyl-CoA C-acetyltransferase.
  
    0.631
tatD-2
Deoxyribonuclease TatD-related protein (TatD).
  
     0.609
TGAM_0459
Conserved hypothetical protein; Belongs to DUF35 family.
  
    0.606
TGAM_1448
Conserved hypothetical protein; Belongs to DUF373 family; 6 probable transmembrane helices predicted by modhmm.
 
     0.556
carS
Conserved hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids.
  
     0.552
TGAM_1344
Conserved hypothetical protein; Belongs to DUF555 family; Belongs to the UPF0212 family.
  
     0.513
dtdA
Conserved hypothetical protein; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
  
     0.478
TGAM_2122
RNA-binding protein, containing PUA domain.
  
     0.478
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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