Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TGAM_0442Radical SAM family protein, lectins/glucanases related. (352 aa)    
Predicted Functional Partners:
TGAM_1450
Conserved hypothetical protein; Belongs to AMMECR1 family.
     0.971
TGAM_1726
Dioxygenase, putative; Contains LigB subunit of an aromatic-ring-opening dioxygenase LigAB signature (SF53213); Belongs to the MEMO1 family.
     0.950
TGAM_0443
Conserved hypothetical protein.
       0.914
TGAM_0439
Conserved hypothetical protein; Belongs to UPF0104 family; 5 probable transmembrane helices predicted by modhmm.
       0.900
TGAM_0441
Polysaccharide deacetylase, putative.
       0.900
TGAM_0444
S-layer protein; 2 probable transmembrane helices predicted by modhmm.
       0.846
TGAM_0445
Conserved hypothetical protein; 1 probable transmembrane helix predicted by modhmm.
       0.846
thiL
Thiamine monophosphate kinase (thiL); Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
       0.812
TGAM_0440
Glycosyltransferase, family 1.
       0.772
TGAM_0434
Phosphoesterase, putative; Contains PHP domain.
       0.697
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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