| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| rpoA1 | rpoA2 | TGAM_1925 | TGAM_1924 | DNA-directed RNA polymerase subunit A' (rpoA1); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit A' (rpoA2); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| rpoA1 | rpoB | TGAM_1925 | TGAM_1926 | DNA-directed RNA polymerase subunit A' (rpoA1); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit B (rpoB); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| rpoA1 | rpoH | TGAM_1925 | TGAM_1927 | DNA-directed RNA polymerase subunit A' (rpoA1); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit H (rpoH); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. | 0.999 |
| rpoA1 | rpoN | TGAM_1925 | TGAM_1962 | DNA-directed RNA polymerase subunit A' (rpoA1); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit N (rpoN); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. | 0.971 |
| rpoA1 | tbp-1 | TGAM_1925 | TGAM_0446 | DNA-directed RNA polymerase subunit A' (rpoA1); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | TATA box-binding protein, transcription initiation factor TFIID (tbp); General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. | 0.836 |
| rpoA1 | tbp-2 | TGAM_1925 | TGAM_0829 | DNA-directed RNA polymerase subunit A' (rpoA1); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | TATA box-binding protein, transcription initiation factor TFIID (tbp); General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. | 0.823 |
| rpoA1 | tfb-1 | TGAM_1925 | TGAM_0475 | DNA-directed RNA polymerase subunit A' (rpoA1); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Transcription initiation factor TFIIB (tfb); Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). | 0.568 |
| rpoA1 | tfb-2 | TGAM_1925 | TGAM_1198 | DNA-directed RNA polymerase subunit A' (rpoA1); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Transcription initiation factor TFIIB (tfb); Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). | 0.575 |
| rpoA1 | tfe | TGAM_1925 | TGAM_0226 | DNA-directed RNA polymerase subunit A' (rpoA1); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Transcription factor TFIIE subunit alpha-like protein (tfe); Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and desta [...] | 0.910 |
| rpoA1 | tfs | TGAM_1925 | TGAM_1048 | DNA-directed RNA polymerase subunit A' (rpoA1); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Transcription elongation factor S (TFS_arch); Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. | 0.868 |
| rpoA2 | rpoA1 | TGAM_1924 | TGAM_1925 | DNA-directed RNA polymerase subunit A' (rpoA2); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit A' (rpoA1); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| rpoA2 | rpoB | TGAM_1924 | TGAM_1926 | DNA-directed RNA polymerase subunit A' (rpoA2); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit B (rpoB); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| rpoA2 | rpoH | TGAM_1924 | TGAM_1927 | DNA-directed RNA polymerase subunit A' (rpoA2); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit H (rpoH); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. | 0.999 |
| rpoA2 | rpoN | TGAM_1924 | TGAM_1962 | DNA-directed RNA polymerase subunit A' (rpoA2); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit N (rpoN); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. | 0.972 |
| rpoA2 | tbp-1 | TGAM_1924 | TGAM_0446 | DNA-directed RNA polymerase subunit A' (rpoA2); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | TATA box-binding protein, transcription initiation factor TFIID (tbp); General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. | 0.865 |
| rpoA2 | tbp-2 | TGAM_1924 | TGAM_0829 | DNA-directed RNA polymerase subunit A' (rpoA2); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | TATA box-binding protein, transcription initiation factor TFIID (tbp); General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. | 0.861 |
| rpoA2 | tfe | TGAM_1924 | TGAM_0226 | DNA-directed RNA polymerase subunit A' (rpoA2); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Transcription factor TFIIE subunit alpha-like protein (tfe); Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and desta [...] | 0.911 |
| rpoA2 | tfs | TGAM_1924 | TGAM_1048 | DNA-directed RNA polymerase subunit A' (rpoA2); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Transcription elongation factor S (TFS_arch); Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. | 0.867 |
| rpoB | rpoA1 | TGAM_1926 | TGAM_1925 | DNA-directed RNA polymerase subunit B (rpoB); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit A' (rpoA1); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| rpoB | rpoA2 | TGAM_1926 | TGAM_1924 | DNA-directed RNA polymerase subunit B (rpoB); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit A' (rpoA2); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |