Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
TGAM_0458Hypothetical protein. (54 aa)    
Predicted Functional Partners:
vapC-2
Nucleotide binding protein, putative, containing PIN domain; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
       0.874
TGAM_0459
Conserved hypothetical protein; Belongs to DUF35 family.
       0.755
TGAM_0460
Acetyl-CoA C-acetyltransferase.
       0.755
TGAM_0461
3-hydroxy-3-methylglutaryl CoA synthase; Belongs to the thiolase-like superfamily. UPF0219 family.
       0.753
TGAM_0462
Conserved hypothetical protein; Contains DUF124 domain.
       0.459
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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