close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gar1Gar1-like small nucleolar rnp, putative (gar1). (99 aa)    
Predicted Functional Partners:
nop10
Nucleolar RNA-binding protein, Nop10p family; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.
   
 0.999
truB
Centromere binding protein CBF5/pseudouridine synthase truB-like protein (truB); Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
   
 0.999
rpl7AE
LSU ribosomal protein L7AE (rpl7AE); Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
 
 0.988
TGAM_0464
pre-mRNA splicing, snoRNA binding protein, NOP5/NOP56 related.
 
 
 0.916
tfb-1
Transcription initiation factor TFIIB (tfb); Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
 
  
 0.855
TGAM_0476
Metal-dependent phosphoesterase, putative.
 
     0.814
TGAM_2004
Conserved hypothetical protein; Belongs to DUF171 family.
  
   0.730
TGAM_0279
Ribosome subunit biogenesis protein, putative; Belongs to UPF0113 family.
  
 
 0.678
TGAM_0745
Conserved hypothetical protein; Contains band 7 domain of flotillin (reggie) like proteins; 2 probable transmembrane helices predicted by modhmm.
  
     0.625
guaA_C
GMP synthase [glutamine-hydrolyzing] pyrophosphatase subunit (C terminal domain) (guaA_C); Catalyzes the synthesis of GMP from XMP.
  
  
 0.619
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.