STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phoU-2Phosphate uptake regulator, phoU and SpoVT/AbrB family (phoU). (304 aa)    
Predicted Functional Partners:
pstA
ABC-type phosphate transport system, permease component (pstA); 5 probable transmembrane helices predicted by modhmm.
 
  
 0.852
pstB
ABC-type phosphate transport system, ATPase component (pstB); Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
 
  
 0.846
dtdA
Conserved hypothetical protein; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
 
     0.838
TGAM_1413
Tetracycline resistance protein, putative, major facilitator superfamily; 12 probable transmembrane helices predicted by modhmm.
 
  
 0.704
TGAM_0480
Periplasmic binding protein; Duplicated PF01497 domains; 1 probable transmembrane helix predicted by modhmm.
     
 0.694
ribK
Transcription regulator, putative; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.
  
     0.654
TGAM_1412
Biotin synthase related protein.
       0.649
asnA
L-asparaginase (asnA).
       0.649
pstS
ABC-type phosphate transport system, periplasmic component (PstS); 1 probable transmembrane helix predicted by modhmm; Belongs to the PstS family.
  
  
 0.643
TGAM_1914
Conserved hypothetical protein; Involved in DNA damage repair.
 
     0.560
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.