Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TGAM_0495Signal peptidase I, S26B/S24 family; Serine protease; 4 probable transmembrane helices predicted by modhmm. (352 aa)    
Predicted Functional Partners:
TGAM_2126
Signal peptidase, peptidase S26B; 2 probable transmembrane helices predicted by modhmm.
  
  
  0.916
TGAM_0496
Conserved hypothetical protein; 1 probable transmembrane helix predicted by modhmm.
       0.914
TGAM_0497
Conserved hypothetical protein; 2 probable transmembrane helices predicted by modhmm.
       0.914
TGAM_0103
Signal peptidase, peptidase S26B; 1 probable transmembrane helix predicted by modhmm.
     
  0.900
TGAM_0494
Conserved hypothetical protein; Belongs to DUF1102 family; 1 probable transmembrane helix predicted by modhmm.
       0.860
TGAM_0493
Conserved hypothetical protein; Belongs to DUF1102 family; 1 probable transmembrane helix predicted by modhmm.
       0.852
ppa
Inorganic pyrophosphatase (ppa); Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
  
    0.839
TGAM_0501
Conserved hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
 
     0.827
rps24E
SSU ribosomal protein S24E (rps24E); Belongs to the eukaryotic ribosomal protein eS24 family.
  
    0.784
rpoE1
DNA-directed RNA polymerase subunit E' (rpoE1).
  
    0.781
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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