Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
Experiments
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[Homology]
Score
TGAM_0507Conserved hypothetical protein. (152 aa)    
Predicted Functional Partners:
tdk
Thymidine kinase (tdk).
       0.899
nefD-1
Nodulation efficiency protein D related protein (nefD); Belongs to DUF107 family; 3 probable transmembrane helices predicted by modhmm.
       0.760
TGAM_0510
Prohibitin/Stomatin-like protein; 1 probable transmembrane helix predicted by modhmm.
       0.760
TGAM_0505
Conserved hypothetical protein; Belongs to UPF0128 family.
       0.649
rps17E
SSU ribosomal protein S17E (rps17E); Belongs to the eukaryotic ribosomal protein eS17 family.
       0.649
tfe
Transcription factor TFIIE subunit alpha-like protein (tfe); Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and desta [...]
  
     0.618
ttuD
Hydroxypyruvate reductase (ttuD).
       0.542
rnp4
Ribonuclease P protein component 4 (rnp4); Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
 
     0.533
TGAM_0511
Conserved hypothetical protein; 1 probable transmembrane helix predicted by modhmm.
       0.477
aeF1-B
Translation elongation factor aEF-1, subunit beta (aeF1-B); Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
 
     0.469
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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