Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
nefD-1Nodulation efficiency protein D related protein (nefD); Belongs to DUF107 family; 3 probable transmembrane helices predicted by modhmm. (145 aa)    
Predicted Functional Partners:
TGAM_0510
Prohibitin/Stomatin-like protein; 1 probable transmembrane helix predicted by modhmm.
  
 
 0.934
tdk
Thymidine kinase (tdk).
       0.858
TGAM_0507
Conserved hypothetical protein.
       0.760
TGAM_0512
3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase), containing one PUA domain and 2 4Fe-4S binding domains.
       0.652
cobS
Cobalamin (5'-phosphate) synthase (cobS); Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
  
    0.570
TGAM_0511
Conserved hypothetical protein; 1 probable transmembrane helix predicted by modhmm.
       0.561
nfeD
Membrane bound protease, putative, nfeD/ClpP- family (nfeD); 4 probable transmembrane helices predicted by modhmm.
  
  
 0.522
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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