Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pgpAPhosphatidylglycerophosphatase A (PgpA). (136 aa)    
Predicted Functional Partners:
cobS
Cobalamin (5'-phosphate) synthase (cobS); Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
  
 0.967
TGAM_0541
Conserved hypothetical protein.
       0.914
TGAM_0542
N-type ATP pyrophosphatase, putative.
 
     0.911
TGAM_0540
Conserved hypothetical protein.
       0.908
mobA-1
Molybdopterin-guanine dinucleotide biosynthesis protein A, putative (mobA).
 
     0.870
hisC-1
Histidinol-phosphate aminotransferase (hisC).
 
   
 0.860
cobD
Cobalamin biosynthesis protein (cobD); Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
   
 0.858
TGAM_0543
Uracil-DNA glycosylase superfamily protein.
  
    0.834
TGAM_0605
Conserved hypothetical protein; Belongs to UPF0146 family.
  
     0.589
hisI
Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase (HisI); In the N-terminal section; belongs to the PRA-CH family.
       0.550
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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