Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
TGAM_0573Conserved hypothetical protein; 2 probable transmembrane helices predicted by modhmm. (336 aa)    
Predicted Functional Partners:
TGAM_0574
Calcineurin-like family phosphoesterase, putative.
       0.818
TGAM_0572
Conserved hypothetical protein; 1 probable transmembrane helix predicted by modhmm.
       0.672
TGAM_0331
Solute binding protein, putative; Contains Periplasmic binding protein-like II domain (SSF53850); 2 probable transmembrane helices predicted by modhmm.
  
     0.621
TGAM_1847
Conserved hypothetical protein.
  
     0.571
phoU-2
Phosphate uptake regulator, phoU and SpoVT/AbrB family (phoU).
  
     0.458
TGAM_0117
Protein kinase, putative; Contains protein kinase-like (SSF56112) domain.
  
     0.452
TGAM_0866
Conserved hypothetical protein; Belongs to DUF81 family; Belongs to the UPF0201 family.
 
     0.442
TGAM_1092
Dolichyl-phosphate-mannose-protein mannosyltransferase, putative; 8 probable transmembrane helices predicted by modhmm.
  
     0.429
TGAM_0406
Oligosaccharyl transferase STT3 subunit; 10 probable transmembrane helices predicted by modhmm.
  
     0.428
TGAM_1662
Metallophosphoesterase; 2 probable transmembrane helices predicted by modhmm.
  
     0.423
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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