Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lhr-1ATP-dependent helicase, lhr-like protein (lhr). (874 aa)    
Predicted Functional Partners:
TGAM_0574
Calcineurin-like family phosphoesterase, putative.
 
    0.747
TGAM_0575
Conserved hypothetical protein.
       0.584
TGAM_1687
mRNA 3-end processing factor, putative; Contains 1 Metallo-hydrolase/oxidoreductase fold (SSF56281).
 
    0.574
lig
ATP-dependent DNA ligase (lig); DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair; Belongs to the ATP-dependent DNA ligase family.
 
    0.556
TGAM_0957
Calcineurin-like phosphoesterase, exonuclease sbcD related protein.
 
    0.401
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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