Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TGAM_0627Conserved hypothetical protein; 2 probable transmembrane helices predicted by modhmm. (133 aa)    
Predicted Functional Partners:
TGAM_0625
Conserved hypothetical protein; 2 probable transmembrane helices predicted by modhmm.
       0.801
TGAM_0626
Conserved hypothetical protein; 6 probable transmembrane helices predicted by modhmm.
       0.801
TGAM_0628
ABC-type transport protein, ATPase component.
       0.773
nadC-2
Nicotinate-nucleotide pyrophosphorylase (Quinolinate phosphoribosyltransferase) (nadC); Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.
       0.575
pdxS
Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
       0.479
pdxT
Glutamine amidotransferase subunit pdxT (pdxT); Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
       0.423
TGAM_0623
Sugar-phosphate nucleotydyltransferase.
       0.415
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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