Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
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gene co-occurrence
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[Homology]
Score
TGAM_0643Undecaprenol kinase related protein; 7 probable transmembrane helices predicted by modhmm. (244 aa)    
Predicted Functional Partners:
TGAM_0641
Conserved hypothetical protein; Belongs to DUF835 family; 7 probable transmembrane helices predicted by modhmm.
       0.914
TGAM_0642
Sugar-phosphate nucleotydyltransferase.
       0.914
TGAM_0645
GTPase, NOG1/MMR-HSR1 family; Belongs to G-protein superfamily.
       0.790
rnz
Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.
  
  
 0.660
pyrH
Uridylate kinase (pyrH); Catalyzes the reversible phosphorylation of UMP to UDP.
    
 0.652
TGAM_0558
Metal-dependent hydrolase/oxidoreductase, beta-lactamase family.
       0.639
pyrG
CTP synthase (pyrG); Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
 
 0.637
nrdA
Ribonucleoside-diphosphate reductase alpha subunit (nrdA); Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
    
  0.567
TGAM_0644
Hypothetical protein; 2 probable transmembrane helices predicted by modhmm.
       0.559
uppS
Undecaprenyl pyrophosphate synthetase (Di-trans-poly-cis-decaprenylcistransferase) (uppS); Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
     
 0.546
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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