Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
apu-2Amylopullulanase, putative (Apu); 2 probable transmembrane helices predicted by modhmm. (975 aa)    
Predicted Functional Partners:
TGAM_0688
Methyltransferase C-terminus, putative; Possibly a frameshift with tg0689.
       0.556
TGAM_0689
Methyltransferase N-terminus, putative; Possibly a frameshift with tg0688.
       0.556
TGAM_0687
Conserved hypothetical protein; 2 probable transmembrane helices predicted by modhmm.
       0.538
TGAM_0691
GTPase, MMR-HSR1 family; Belongs to G-protein superfamily. Contains 1 TGS domain.
       0.507
TGAM_0685
Conserved hypothetical protein.
       0.455
TGAM_0686
Conserved hypothetical protein.
       0.455
eRF1
Peptide chain release factor eRF/aRF, subunit 1 (eRF1/prf1); Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
       0.412
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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