Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
TGAM_0697Lipoate-protein ligase A. (323 aa)    
Predicted Functional Partners:
TGAM_0102
lplA-like lipoate-protein ligase A related.
 
 
 0.991
TGAM_0699
Conserved membrane protein; Belongs to DUF95 family; 5 probable transmembrane helices predicted by modhmm.
       0.892
gcvH
Glycine cleavage system protein H (gcvH); The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
   
 0.771
argS
Arginyl-tRNA synthetase (argS); Belongs to the class-I aminoacyl-tRNA synthetase family.
  
    0.657
TGAM_0081
Radical SAM family protein.
 
     0.611
TGAM_1412
Biotin synthase related protein.
 
     0.589
TGAM_1862
Conserved hypothetical protein; Belongs to DUF998 family; 6 probable transmembrane helices predicted by modhmm.
 
     0.451
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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