Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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uppSUndecaprenyl pyrophosphate synthetase (Di-trans-poly-cis-decaprenylcistransferase) (uppS); Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids. (264 aa)    
Predicted Functional Partners:
idsA
Bifunctional short chain isoprenyl diphosphate synthase (idsA); Belongs to the FPP/GGPP synthase family.
 
 
 0.970
TGAM_0718
Carbonic anhydrase/acetyltransferase, containing bacterial transferase hexapeptide repeat.
     
 0.916
ftsZ-1
Cell division GTPase, ftsZ-like protein (ftsZ); Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
  
 0.851
ftsZ-3
Cell division GTPase, ftsZ-like protein (ftsZ); Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
  
 0.851
TGAM_0716
Conserved hypothetical protein; 2 probable transmembrane helices predicted by modhmm.
       0.833
hjc
Archaeal holliday junction resolvase (Hjc); A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products; Belongs to the Holliday junction resolvase Hjc family.
       0.833
TGAM_0008
Conserved hypothetical protein; 2 probable transmembrane helices predicted by modhmm.
      
 0.783
pyrH
Uridylate kinase (pyrH); Catalyzes the reversible phosphorylation of UMP to UDP.
  
  
 0.706
valS
Valyl-tRNA synthetase (valS); Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
 
  
 0.695
TGAM_1240
Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
  
 0.670
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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