Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TGAM_0738Divalent cation transporter, MgtE-like protein; Contains 2 MgtE integral membrane regions; 9 probable transmembrane helices predicted by modhmm. (397 aa)    
Predicted Functional Partners:
TGAM_0737
Potassium transport regulation protein, PhoU/TrkA-C related; Contains 1 PhoU domain in Nterm and 1 TrkA-C domain in Cterm.
 
     0.882
TGAM_0736
Potassium transport regulation protein, PhoU/TrkA-C related; Contains 1 PhoU domain in Nterm and 1 TrkA-C domain in Cterm.
 
     0.881
nfo
Deoxyribonuclease IV (BER) (Nfo); May be also related to Xylose isomerase.
       0.721
TGAM_0739
Divalent cation transporter, MgtE-like protein; Contains 2 MgtE integral membrane regions; 9 probable transmembrane helices predicted by modhmm.
 
    
0.657
acdA-4
Acetyl-CoA synthetase (ADP forming), alpha chain (acdA).
       0.586
acdB-1
Acetyl-CoA synthetase (ADP forming), beta chain (acdB).
       0.553
TGAM_2123
Conserved hypothetical protein; Contains probably 1 tRNA-binding domain (SSF46589) in Nterm and 1 t-snare domain (SSF47661) in Cterm.
  
     0.437
TGAM_0326
TRP-repeat-containing protein; 4 probable transmembrane helices predicted by modhmm.
  
     0.423
TGAM_2004
Conserved hypothetical protein; Belongs to DUF171 family.
  
     0.405
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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