Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nefD-2Nodulation efficiency protein D related protein (nefD); 2 probable transmembrane helices predicted by modhmm. (136 aa)    
Predicted Functional Partners:
TGAM_0781
Zinc-dependent protease, putative.
       0.822
TGAM_0780
Radical SAM domain protein.
       0.581
cobS
Cobalamin (5'-phosphate) synthase (cobS); Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
  
    0.570
nfeD
Membrane bound protease, putative, nfeD/ClpP- family (nfeD); 4 probable transmembrane helices predicted by modhmm.
  
  
 0.522
TGAM_1901
Membrane permease, stomatin-like protein; 1 probable transmembrane helix predicted by modhmm.
 
 
 0.462
blaI
Penicillinase repressor-like protein (BlaI).
 
     0.414
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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