Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
TGAM_0787RNA methylase, putative; Belongs to UPF0020 family. (366 aa)    
Predicted Functional Partners:
TGAM_0788
Protein prenyltransferase, putative; Contains Protein prenylyltransferase (SSF48439) domain.
       0.834
TGAM_0790
Conserved hypothetical protein; Belongs to UPF0047 family.
       0.804
TGAM_0786
Conserved hypothetical protein.
       0.704
TGAM_0789
Conserved hypothetical protein.
       0.610
TGAM_0852
Nonsense-mediated mRNA decay protein, NMD3-like protein.
  
    0.609
TGAM_1498
Brix-domain ribosomal biogenesis protein; Probably involved in the biogenesis of the ribosome.
  
    0.604
TGAM_0504
Methylase, putative, hemK and PrmA related; Location of this gene downstream of S24E and S27AE ribosomal proteins suggests it might be ribosomal protein L11 methyltransferase (PrmA).
    
 
 0.571
TGAM_0645
GTPase, NOG1/MMR-HSR1 family; Belongs to G-protein superfamily.
 
    0.524
TGAM_1749
Conserved hypothetical protein; Possibly a cell adhesion protein. Contains 9 APHP/CARDB and 2 PKD domains; 1 probable transmembrane helix predicted by modhmm.
  
     0.517
TGAM_1102
Predicted ATPase of the PP-loop superfamily.
  
  
 0.512
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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