Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fecD-1Iron(III) dicitrate transport system permease protein (fecD); 8 probable transmembrane helices predicted by modhmm. (344 aa)    
Predicted Functional Partners:
fecE-1
Iron(III) dicitrate ABC transporter, ATP-binding protein (fecE).
 
 
 0.993
TGAM_0821
Iron transport ABC protein, periplasmic component; 1 probable transmembrane helix predicted by modhmm.
 
 
 0.984
fecE-2
Iron(III) dicitrate ABC transporter, ATP-binding protein (fecE).
 
 
 0.923
TGAM_0480
Periplasmic binding protein; Duplicated PF01497 domains; 1 probable transmembrane helix predicted by modhmm.
 
 
 0.891
glkA
ADP-dependent glucokinase (glkA); Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ADP as the phosphate donor.
       0.616
cooC-2
Carbon monoxide dehydrogenase accessory protein, putative (cooC).
       0.561
cooS
Carbon monoxide dehydrogenase (cooS).
     
 0.472
manA
Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyl transferase, bifunctional enzyme (manA/manC); Belongs to the mannose-6-phosphate isomerase type 2 family.
     
 0.468
TGAM_0814
Hypothetical protein; 3 probable transmembrane helices predicted by modhmm.
       0.450
mngB
Mannosyl-3-phosphoglycerate phosphatase (mngB); HAD-superfamily hydrolase YedP.
       0.450
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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