Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
czcDCation efflux system protein (czcD); 5 probable transmembrane helices predicted by modhmm. (299 aa)    
Predicted Functional Partners:
TGAM_0833
ABC-type transport system, ATPase component, putative multidrug/lipooligosaccharide transporter.
  
 
 0.627
hypA
[NiFe] hydrogenase maturation protein (hypA); Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
     
 0.589
TGAM_1853
Bifunctional phosphosugar nucleotidyltransferase/CDP-alcohol phosphatidyltransferase; 2 probable transmembrane helices predicted by modhmm; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
    0.582
TGAM_0831
Conserved hypothetical protein; 6 probable transmembrane helices predicted by modhmm.
       0.573
TGAM_0832
Conserved hypothetical protein; 5 probable transmembrane helices predicted by modhmm.
       0.573
zupT
Heavy metal ion transport protein, putative ZIP-type Zinc transporter (zupT); 7 probable transmembrane helices predicted by modhmm.
  
 0.519
TGAM_0234
PP-loop ATPase, mrp-like protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
  
  
 0.509
atpI
Archaeal/vacuolar-type H+-ATPase subunit I (atpI); 7 probable transmembrane helices predicted by modhmm; Belongs to the V-ATPase 116 kDa subunit family.
   
 
 0.507
tbp-2
TATA box-binding protein, transcription initiation factor TFIID (tbp); General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
  
    0.496
osmC-1
OsmC-like stress-induced protein (OsmC).
 
     0.438
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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