Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TGAM_0853Conserved hypothetical protein; Belongs to DUF424 family. (101 aa)    
Predicted Functional Partners:
TGAM_0852
Nonsense-mediated mRNA decay protein, NMD3-like protein.
       0.878
TGAM_1424
RNA-binding protein, containing KH domain.
 
     0.668
TGAM_1050
NAD(P)H sulfur oxidoreductase.
       0.649
cdc6
Cell division control protein 6-like protein (cdc6); Involved in regulation of DNA replication.
  
     0.621
ribK
Transcription regulator, putative; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.
  
     0.616
TGAM_1914
Conserved hypothetical protein; Involved in DNA damage repair.
  
     0.616
TGAM_0471
Metal-dependant protease, putative; Belongs to Mov34/MPN/PAD-1 family Contains Jab1/MPN domain.
  
     0.604
TGAM_0854
Bacterial regulatory protein, arsR family.
       0.604
dtdA
Conserved hypothetical protein; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
  
     0.562
nac
Nascent polypeptide-associated complex protein (nac); Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
  
     0.532
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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