Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
amzAZinc-dependent protease, archaeal type, predicted; Probable zinc metalloprotease whose natural substrate is unknown. (191 aa)    
Predicted Functional Partners:
cyaB-1
Adenylate cyclase type 2, thermophiic (CyaB).
 
     0.924
TGAM_0858
Conserved hypothetical protein.
       0.914
TGAM_0861
M42 family glutamyl aminopeptidase, de-blocking aminopeptidase.
       0.874
TGAM_0716
Conserved hypothetical protein; 2 probable transmembrane helices predicted by modhmm.
       0.603
hjc
Archaeal holliday junction resolvase (Hjc); A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products; Belongs to the Holliday junction resolvase Hjc family.
       0.597
rps3AE
SSU ribosomal protein S3AE (rps3AE); Belongs to the eukaryotic ribosomal protein eS1 family.
       0.482
TGAM_0863
Conserved hypothetical protein.
       0.466
recJ
recJ-like single-stranded exonuclease recJ-like protein (recJ).
       0.466
TGAM_0910
Putative transcription regulator.
  
     0.430
rps15P
SSU ribosomal protein S15P (rps15P).
       0.425
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.