Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TGAM_0868Adenylate/cytidine kinase related protein; Belongs to the UPF0200 family. (190 aa)    
Predicted Functional Partners:
hel308
Ski2-type helicase, putative; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
     
 0.651
coaD
Phosphopantetheine adenylyltransferase (coaD); Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the eukaryotic CoaD family.
    
 0.600
TGAM_0869
Conserved hypothetical protein; 3 probable transmembrane helices predicted by modhmm.
       0.571
TGAM_0866
Conserved hypothetical protein; Belongs to DUF81 family; Belongs to the UPF0201 family.
 
    0.548
TGAM_0166
Nucleic acid-binding protein, containing OB-fold domain.
  
     0.507
rnhB
Ribonuclease HII (rnhB); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
  
    0.494
TGAM_0501
Conserved hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
  
   
 0.489
hisI
Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase (HisI); In the N-terminal section; belongs to the PRA-CH family.
       0.472
TGAM_0403
Conserved hypothetical protein; Contains DUF137 domain.
 
     0.443
TGAM_0647
DEAD/DEAH box RNA helicase.
 
     0.403
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
Server load: low (14%) [HD]