Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TGAM_0895Cytochrome-c3 hydrogenase, gamma subunit. (295 aa)    
Predicted Functional Partners:
gltA-2
Glutamate synthase (NADPH), homotetrameric (gltA).
 
 
 0.998
gltA-1
Glutamate synthase (NADPH), homotetrameric (gltA).
 
 
 0.995
gltD-1
Glutamate synthase [NADPH] small chain (gltD).
 
 
 0.874
pyrD
Dihydroorotase dehydrogenase (pyrD); Catalyzes the conversion of dihydroorotate to orotate.
 
 
 0.863
gltD-2
Glutamate synthase [NADPH] small chain (gltD).
 
 
 0.821
gltD-3
Glutamate synthase [NADPH] small chain (gltD).
 
 
 0.721
pyrF
Orotidine 5'-phosphate decarboxylase (pyrF); Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
  
 0.674
pyrE
Orotate phosphoribosyltransferase (pyrE); Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
  
 0.674
pyrB
Aspartate carbamoyltransferase, catalytic subunit (pyrB).
  
  
 0.666
pyrC
Dihydroorotase (pyrC); Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
  
  
 0.612
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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