Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
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gcvHGlycine cleavage system protein H (gcvH); The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (134 aa)    
Predicted Functional Partners:
gcvT
Glycine cleavage system T protein (aminomethyltransferase) (gcvT); The glycine cleavage system catalyzes the degradation of glycine.
 
 0.999
gcvP2
Glycine dehydrogenase [decarboxylating] subunit 2 (glycine cleavage system P- protein) (gcvP2); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.
 
 0.999
gcvP1
Glycine dehydrogenase [decarboxylating] subunit 1 (glycine cleavage system P- protein) (gcvP1); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
 
 0.995
glyA
Serine hydroxymethyltransferase (glyA); Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
 
 
 0.976
TGAM_0902
Conserved hypothetical protein.
       0.914
aat
Alanine aminotransferase (aat).
  
 
 0.910
TGAM_1056
Multiple substrate aminotransferase; Belongs to class I.
     
  0.900
TGAM_0102
lplA-like lipoate-protein ligase A related.
 
 
 0.848
glnA
Glutamine synthetase (glnA).
  
 
 0.846
purQ
Phosphoribosylformylglycinamidine synthase I, purQ component (purQ); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and [...]
  
 
  0.828
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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