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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TGAM_0905Conserved hypothetical protein; Belongs to DUF655 family; Contains DNA polymerase beta, N-terminal-like domain. (206 aa)    
Predicted Functional Partners:
rpl21E
LSU ribosomal protein L21E (rpl21E); Belongs to the eukaryotic ribosomal protein eL21 family.
 
  
 0.883
ksgA
Ribosomal RNA adenine methylase transferase (Dimethyladenosine transferase) (ksgA); Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
     
 0.840
dnaG
Primase-related protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
  
   
 0.743
rpoF
DNA-directed RNA polymerase subunit F (rpoF).
 
   
 0.721
gcvH
Glycine cleavage system protein H (gcvH); The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
       0.702
TGAM_0902
Conserved hypothetical protein.
       0.688
cca
tRNA nucleotidyltransferase (CCA adding enzyme) (cca); Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
 
   
 0.678
nac
Nascent polypeptide-associated complex protein (nac); Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
  
     0.663
dp2
DNA polymerase II large subunit DP2, intein containing (dp2/polC); Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.
  
     0.652
rpoE2
DNA-directed RNA polymerase subunit E' (rpoE2); Stimulates transcription elongation; Belongs to the archaeal Spt4 family.
  
     0.647
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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