Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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TGAM_0919Nucleotide binding protein, putative, containing PIN domain. (143 aa)    
Predicted Functional Partners:
gatD-1
L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D (gatD); Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
       0.798
TGAM_0918
Conserved hypothetical protein; Belongs to DUF104 family.
       0.798
gatE
Archaeal Glu-tRNAGln amidotransferase subunit E (gatE); Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
       0.798
TGAM_0913
Hypothetical protein; Contains 1 PRC-barrel domain; 6 probable transmembrane helices predicted by modhmm.
       0.565
nfi
Endonuclease V (Deoxyinosine 3' endonuclease) (nfi); DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
       0.565
TGAM_0916
RNA-binding protein, translin-like protein.
       0.565
ribK
Transcription regulator, putative; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.
       0.548
TGAM_0912
Conserved hypothetical protein; Contains 1 PRC-barrel domain.
       0.474
TGAM_0921
Glycosyltransferase, family 2; 4 probable transmembrane helices predicted by modhmm.
       0.428
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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