Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hitHistidine triad (HIT) protein (hit). (165 aa)    
Predicted Functional Partners:
TGAM_2041
Hit histidine triad protein (hit).
  
  
 
0.908
TGAM_0924
Hypothetical protein; 3 probable transmembrane helices predicted by modhmm.
       0.712
apgM
2,3-bisphosphoglycerate-independent phosphoglycerate mutase (apgM); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
       0.649
TGAM_1334
Ca2+/Na+ antiporter; 10 probable transmembrane helices predicted by modhmm.
  
    0.534
hisI
Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase (HisI); In the N-terminal section; belongs to the PRA-CH family.
  
    0.527
glnA
Glutamine synthetase (glnA).
  
   0.523
npdA
NAD-dependent protein deacetylase, Sir2 family (npdA); Belongs to the sirtuin family. Class III subfamily.
  
 
  0.483
TGAM_1853
Bifunctional phosphosugar nucleotidyltransferase/CDP-alcohol phosphatidyltransferase; 2 probable transmembrane helices predicted by modhmm; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
  
 0.455
TGAM_0925
Met-10 like-protein, putative SAM-dependent methyltransferase.
  
    0.423
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
Server load: low (26%) [HD]