Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TGAM_0937Oligosaccharyl transferase, STT3 subunit; 13 probable transmembrane helices predicted by modhmm. (993 aa)    
Predicted Functional Partners:
glmS-2
Glucosamine--fructose-6-phosphate aminotransferase (isomerizing) (glmS); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
  
 0.918
TGAM_1749
Conserved hypothetical protein; Possibly a cell adhesion protein. Contains 9 APHP/CARDB and 2 PKD domains; 1 probable transmembrane helix predicted by modhmm.
 
     0.721
TGAM_1498
Brix-domain ribosomal biogenesis protein; Probably involved in the biogenesis of the ribosome.
  
 
   0.664
TGAM_0661
Conserved hypothetical protein; 3 probable transmembrane helices predicted by modhmm.
  
     0.651
rpl35AE
LSU ribosomal protein L35AE (rpl35AE); Belongs to the eukaryotic ribosomal protein eL33 family.
  
 
   0.650
TGAM_1094
Conserved hypothetical protein.
       0.649
rpl22P
LSU ribosomal protein L22P (rpl22P); The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
 
   0.646
TGAM_1675
Arginase related protein; Belongs to the arginase family.
 
     0.640
TGAM_0935
Hypothetical protein; 3 probable transmembrane helices predicted by modhmm.
       0.613
rpl32E
LSU ribosomal protein L32E (rpl32E); Belongs to the eukaryotic ribosomal protein eL32 family.
  
   0.609
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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