Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
arsAArsenical pump-driving ATPase (arsA). (336 aa)    
Predicted Functional Partners:
TGAM_0944
Conserved hypothetical protein.
 
     0.955
TGAM_0947
Conserved hypothetical protein; 1 probable transmembrane helix predicted by modhmm.
 
     0.944
TGAM_0946
Conserved hypothetical protein.
       0.914
cstA
Carbon starvation protein A (cstA); 14 probable transmembrane helices predicted by modhmm.
 
     0.912
TGAM_0943
Conserved hypothetical protein.
       0.905
TGAM_0950
Lysophospholipase, putative.
       0.853
pyrF
Orotidine 5'-phosphate decarboxylase (pyrF); Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
    
 
 0.820
TGAM_0949
Nucleotide binding protein, putative, containing PIN domain.
       0.761
pycB
Pyruvate carboxylase subunit B (pycB).
  
    0.658
TGAM_0471
Metal-dependant protease, putative; Belongs to Mov34/MPN/PAD-1 family Contains Jab1/MPN domain.
   
   0.616
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.