Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
Experiments
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[Homology]
Score
TGAM_0955Transcription regulator, putative; Contains 1 HTH domain, 1 CBS domain pair. (195 aa)    
Predicted Functional Partners:
pfdA-1
Prefoldin alpha subunit (pfdA); Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
 
     0.845
TGAM_1415
Membrane protein, putative; Contains 1 DUF6 domain; 7 probable transmembrane helices predicted by modhmm.
     
 0.758
TGAM_0954
Hypothetical protein; 2 probable transmembrane helices predicted by modhmm.
       0.553
TGAM_0975
Transcription regulator, HTH/deoR family.
       0.480
TGAM_0480
Periplasmic binding protein; Duplicated PF01497 domains; 1 probable transmembrane helix predicted by modhmm.
       0.428
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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