Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TGAM_0970WD40-domain containing protein; 1 probable transmembrane helix predicted by modhmm. (3037 aa)    
Predicted Functional Partners:
TGAM_1687
mRNA 3-end processing factor, putative; Contains 1 Metallo-hydrolase/oxidoreductase fold (SSF56281).
  
 
 0.814
TGAM_0968
Serine/threonine protein kinase; 2 probable transmembrane helices predicted by modhmm.
 
 
0.807
TGAM_0966
ATPase of the AAA family.
  
 
 0.806
TGAM_0429
Acetylpolyamine amidohydrolase, histone deacetylase superfamily.
   
 0.783
TGAM_0974
Serine/threonine protein kinase.
 
 
0.738
pp2C
Serine/threonine protein phosphatase 2C (PP2C); 2 probable transmembrane helices predicted by modhmm.
  
 
 0.722
TGAM_0972
ATPase of the AAA family.
  
 
 0.718
TGAM_0201
GTP-binding protein, HSR1-related GTPase; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
  
 0.713
TGAM_0979
Serine/threonine protein kinase; 1 probable transmembrane helix predicted by modhmm.
 
 
 0.693
TGAM_1623
Type III restriction endonuclease, res subunit; Belongs to DEAD-like/ SNF2 superfamily. mod subunit is tg1624.
   
 0.687
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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