Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TGAM_0975Transcription regulator, HTH/deoR family. (498 aa)    
Predicted Functional Partners:
TGAM_0977
Prokaryotic ATPase, AAA superfamily, disease resistance protein related; Contains Archaeal ATPase domain (PF01637) Contains Disease resistance protein signature (IPR000767).
 
     0.822
TGAM_0976
Hypothetical protein.
       0.775
TGAM_0978
Prokaryotic ATPase, AAA superfamily; Contains Archaeal ATPase domain (PF01637).
 
     0.746
TGAM_1621
Resolvase, putative.
     
 0.708
TGAM_1842
ATPase involved in chromosome partitioning, minD/ParA family.
 
   
 0.706
TGAM_1658
DNA repair helicase, XPB-rad25 -like protein.
 
     0.701
TGAM_0973
Voltage-gated potassium channel, putative; 2 probable transmembrane helices predicted by modhmm.
       0.689
TGAM_0979
Serine/threonine protein kinase; 1 probable transmembrane helix predicted by modhmm.
 
   
 0.672
TGAM_0974
Serine/threonine protein kinase.
 
   
0.670
TGAM_1623
Type III restriction endonuclease, res subunit; Belongs to DEAD-like/ SNF2 superfamily. mod subunit is tg1624.
       0.649
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
Server load: low (14%) [HD]