Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pp2CSerine/threonine protein phosphatase 2C (PP2C); 2 probable transmembrane helices predicted by modhmm. (864 aa)    
Predicted Functional Partners:
TGAM_0981
Serine/threonine protein kinase.
 
 0.972
TGAM_0979
Serine/threonine protein kinase; 1 probable transmembrane helix predicted by modhmm.
 
 0.950
TGAM_0968
Serine/threonine protein kinase; 2 probable transmembrane helices predicted by modhmm.
 
 0.946
TGAM_0989
Serine/threonine protein kinase; 1 probable transmembrane helix predicted by modhmm.
 
 0.919
TGAM_0974
Serine/threonine protein kinase.
 
 0.916
TGAM_0429
Acetylpolyamine amidohydrolase, histone deacetylase superfamily.
 
 
 0.855
TGAM_0799
Serine/threonine protein kinase, putative S-layer protein; Contains 1 beta-propeller YVTN-type domain in Nterm, 1 PEGA domain in central part and 1 protein kinase domain in Cterm; 2 probable transmembrane helices predicted by modhmm.
 
 0.849
TGAM_1460
recJ-like phosphoesterase, containing RNA binding S1 and OB-fold nucleic acid binding domain.
  
 
 0.836
pcp
Pyrrolidone-carboxylate peptidase (pcp); Removes 5-oxoproline from various penultimate amino acid residues except L-proline; Belongs to the peptidase C15 family.
    
   0.808
ndk
Nucleoside diphosphate kinase (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
   
 
 0.804
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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