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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pp2CSerine/threonine protein phosphatase 2C (PP2C); 2 probable transmembrane helices predicted by modhmm. (864 aa)    
Predicted Functional Partners:
TGAM_0981
Serine/threonine protein kinase.
 
 0.968
gcvT
Glycine cleavage system T protein (aminomethyltransferase) (gcvT); The glycine cleavage system catalyzes the degradation of glycine.
   
 0.945
TGAM_0979
Serine/threonine protein kinase; 1 probable transmembrane helix predicted by modhmm.
 0.943
TGAM_0974
Serine/threonine protein kinase.
 
 0.904
TGAM_0989
Serine/threonine protein kinase; 1 probable transmembrane helix predicted by modhmm.
 
 0.898
TGAM_0968
Serine/threonine protein kinase; 2 probable transmembrane helices predicted by modhmm.
 
 0.893
TGAM_0799
Serine/threonine protein kinase, putative S-layer protein; Contains 1 beta-propeller YVTN-type domain in Nterm, 1 PEGA domain in central part and 1 protein kinase domain in Cterm; 2 probable transmembrane helices predicted by modhmm.
 
 0.828
TGAM_0982
Hypothetical protein, S-layer-like related; 3 probable transmembrane helices predicted by modhmm.
       0.714
TGAM_1460
recJ-like phosphoesterase, containing RNA binding S1 and OB-fold nucleic acid binding domain.
  
 
 0.606
TGAM_1454
SAM-dependent tRNA/rRNA cytosine-C5 methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
 
  
 0.601
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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