Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fbpBABC-type Fe3+ transport system permease component (fbpB/AfuB); 12 probable transmembrane helices predicted by modhmm. (557 aa)    
Predicted Functional Partners:
TGAM_1016
ABC-type Fe3+ transport system, periplasmic component (fbpA/afuA); 2 probable transmembrane helices predicted by modhmm.
 
 
 0.993
fbpC
ABC-type transport system, ATPase component, putative Fe3+ transporter (fbpC/afuC).
 
 
 0.979
TGAM_1088
ABC-type transport system, periplasmic component; 1 probable transmembrane helix predicted by modhmm.
 
 
 0.947
modB
Duplicated BPD (PF00528) domain separated by a large 124 aa insertion at pos. 385; 9 probable transmembrane helices predicted by modhmm.
  
  
 
0.928
fbpC-2
ABC-type transport system, ATPase component, putative Fe3+ transporter (fbpC/afuC).
 
 
 0.900
sfuA
ABC-type thiamine transport system, periplasmic component (sfuA); 1 probable transmembrane helix predicted by modhmm.
 
  
 0.784
TGAM_1437
ABC-type transport system, ATPase component, putative molybdate/sulfate transporter.
 
  
 0.553
TGAM_1705
ABC-type transport system, ATPase component, putative Fe3+ transporter; Contains 2 facilitated glucose transporter signatures.
 
  
 0.544
TGAM_1017
Hypothetical protein.
       0.481
TGAM_1018
Short chain dehydrogenase of unknown substrate; Match to IPR002347 Glucose/ribitol dehydrogenase indicates that the protein is not an alcohol dehydrogenase, but another type of dehydrogenase or reductase.
       0.476
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
Server load: low (12%) [HD]