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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfpIPeptidase C56, intracellular protease PfpI family (PfpI). (166 aa)    
Predicted Functional Partners:
rpl40E
LSU ribosomal protein L40E (rpl40E); Belongs to the eukaryotic ribosomal protein eL40 family.
   
 
  0.711
TGAM_1460
recJ-like phosphoesterase, containing RNA binding S1 and OB-fold nucleic acid binding domain.
  
 
 0.681
tyrS
Tyrosyl-tRNA synthetase (tyrS); Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
   
   0.628
TGAM_1072
Putative phosphoglycolate phosphatase fused to dolichol-phosphate mannose synthase (pgp/Dpm1).
  
  
 0.617
TGAM_1071
Transcription regulator, AsnC family.
   
   0.597
rps10P
SSU ribosomal protein S10P (rps10P); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
  
 
 0.580
rpl5P
LSU ribosomal protein L5P (rpl5P); This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
  
 
 0.580
TGAM_1073
Conserved hypothetical protein; 3 probable transmembrane helices predicted by modhmm.
       0.568
rps19P
SSU ribosomal protein S19P (rps19P); Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
  
   0.565
bcp-2
Peroxiredoxin, bacterioferritin comigratory protein-like protein (bcp); Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 
 0.554
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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