Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TGAM_1071Transcription regulator, AsnC family. (169 aa)    
Predicted Functional Partners:
tyrS
Tyrosyl-tRNA synthetase (tyrS); Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
  
    0.915
TGAM_1073
Conserved hypothetical protein; 3 probable transmembrane helices predicted by modhmm.
 
     0.911
TGAM_1072
Putative phosphoglycolate phosphatase fused to dolichol-phosphate mannose synthase (pgp/Dpm1).
       0.782
TGAM_0167
Transcription regulator, Lrp-AsnC family.
  
     0.693
pfpI
Peptidase C56, intracellular protease PfpI family (PfpI).
   
   0.617
TGAM_0647
DEAD/DEAH box RNA helicase.
       0.576
TGAM_0467
Transcription regulator protein, Lrp-Asn family.
  
     0.550
upp
Uracil phosphoribosyltransferase (upp); Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
     
 0.509
TGAM_1088
ABC-type transport system, periplasmic component; 1 probable transmembrane helix predicted by modhmm.
     
 0.414
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
Server load: low (24%) [HD]