Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TGAM_1072Putative phosphoglycolate phosphatase fused to dolichol-phosphate mannose synthase (pgp/Dpm1). (440 aa)    
Predicted Functional Partners:
TGAM_1073
Conserved hypothetical protein; 3 probable transmembrane helices predicted by modhmm.
 
   
 0.944
tyrS
Tyrosyl-tRNA synthetase (tyrS); Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
       0.869
TGAM_1071
Transcription regulator, AsnC family.
       0.782
TGAM_1181
Sucrose-phosphate phosphatase, putative, HAD-superfamily hydrolase; Catalyzes the dephosphorylation of 2-phosphoglycolate.
  
 
 0.769
pgk
Phosphoglycerate kinase (pgk); Belongs to the phosphoglycerate kinase family.
  
 
 0.747
galE-2
UDP-glucose 4-epimerase, putative (galE); Does not match IPR005888 dTDP-glucose 4,6-dehydratase entry.
 
  
 0.729
galE-1
UDP-glucose 4-epimerase (galE).
 
  
 0.702
valS
Valyl-tRNA synthetase (valS); Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
  
  
 0.686
degT
Pleiotropic regulatory protein, pyridoxal-phosphate-dependent aminotransferase (degT); Belongs to the DegT/DnrJ/EryC1 family.
  
  
 0.674
malG
Maltose transport system permease protein (malG); 5 probable transmembrane helices predicted by modhmm.
  
  
 0.663
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.